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This chapter reviews the evidence from social science and medical research that sheds light on this potential immigrant paradox in health -- when, where, and for whom it holds or does not apply. In doing so, two important points need to be kept in mind. First, the existence of the paradox does not necessarily mean that immigrants are doing than everyone else. Rather, it means that they are doing better than social and economic positions suggest that they should be. Second, paradox may apply in general but not hold in specific domains of health for certain subgroups or at certain life stages. The health literature is so voluminous that it cannot be reviewed in its entirety. Instead, this chapter is more selective in its coverage. In line with the developmental and ecological spirit of this book, a particular health topic has been chosen to highlight what is occurring in major periods of the early life course and to demonstrate how physical, social, and cultural forces and contexts intersect to strengthen or weaken the immigrant paradox around this topic. Specifically, the chapter focuses on infant mortality, childhood illness and disease, and adolescent health behavior, giving additional attention to a topic that cuts across life stages: obesity.