Researchers investigated pain perception in patients with diabetic foot ulcers (DFUs) by analyzing pre- and postoperative physical function (PF), pain interference (PI), and depression domains of the Patient-Reported Outcome Measurement Information System (PROMIS). They hypothesized that 1) because of painful diabetic peripheral neuropathy (DPN), a majority of patients with DFUs would have high PROMIS PI scores unchanged by operative intervention, and 2) the initially assessed PI, PF, and depression levels would be correlated with ﬁnal outcomes. Seventy-ﬁve percent of patients with DFUs reported pain, most likely because of painful DPN. Those who reported high PI and low PF were likely to report depression. PF, PI, and depression levels were unchanged after operative intervention or healing of DFUs.
Waldman, Olivia V.; Hao, Stephanie P.; Houck, Jeff R.; Lee, Nicolette J.; Baumhauer, Judith F.; and Oh, Irvin, "Operative Intervention Does Not Change Pain Perception in Patients With Diabetic Foot Ulcers" (2020). Faculty Publications - College of Physical Therapy. 144.
Endocrinology, Diabetes, and Metabolism Commons, Physical Therapy Commons, Podiatry Commons
Originally published in Clinical Diabetes 2020;38(2):132–140