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The FAS BeST was developed by parents and educators of children with Fetal Alcohol Syndrome rating behaviors characteristic of FASD including; easily influenced by others, difficulty learning from experience, appearing and declaring innocence even when confronted with evidence to the contrary, and experiencing difficulties in other domains. The FAS BeST differentiates between children with PEA, dysgenesis of the corpus callosum (DCC), and attention deficit hyperactivity disorder (ADHD; Porter & Andrews, 2004). The sample included 294 participants. Using the cutoff score suggested by Porter and Andrews (2004) the accuracy rates were 78% for FAS/E, 100% for controls, 85% for DCC, and 100% for ADHD. Reliability for the FASD BeST was established for all groups using split-half analysis. Criterion validity was verified using the Achenbach behavioral checklists (2002). A factor analysis indicated the FAS BeST denotes a general factor. The FAS BeST is a reliable and valid measure that is easily administered and scored. Children with PEA can be screened to determine whether further evaluation is warranted and differentiate between disorders with similar behaviors, enabling professionals to better serve the child and assist the care providers.