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Sixty-nine severely and profoundly retarded clients in a residential setting, each of whom could ambulate without staff assistance, were administered the Diagnostic Assessment for the Severely Handicapped (DASH) Scale. Three groups of 23 were selected based on previous psychiatric diagnosis and matched for social age. The group with no psychiatric diagnosis served as the nominal control. The second group contained a mix of non-affective psychiatric diagnoses. The third group contained clients with a diagnosis of bipolar disorder. A one-way analysis of variance was conducted. The data demonstrated the DASH effectively discriminated clients with bipolar disorder from those without psychiatric as well as from non-affective psychiatric disorders. The implications of these findings were discussed, and areas for future study were suggested.